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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYST2
All Species:
22.12
Human Site:
S273
Identified Species:
34.76
UniProt:
O95251
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95251
NP_008998.1
611
70642
S273
E
L
R
K
K
R
N
S
G
L
S
K
E
Q
K
Chimpanzee
Pan troglodytes
XP_511869
806
91579
S468
E
L
R
K
K
R
N
S
G
L
S
K
E
Q
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548192
555
64081
Y234
Y
M
E
H
R
Q
T
Y
G
N
T
R
E
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q5SVQ0
613
70623
S275
E
L
R
K
K
R
N
S
G
L
S
K
E
Q
K
Rat
Rattus norvegicus
Q810T5
612
70496
S274
E
L
R
K
K
R
N
S
G
L
S
K
E
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026512
611
70527
S273
E
L
R
K
K
R
N
S
G
L
S
K
E
Q
K
Frog
Xenopus laevis
NP_001079995
617
71123
L273
Y
K
E
K
V
T
E
L
R
K
K
R
N
S
G
Zebra Danio
Brachydanio rerio
NP_997800
568
65560
T247
K
Y
M
E
H
R
Q
T
H
G
T
T
R
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q960X4
541
61216
L220
V
H
V
T
G
D
G
L
I
S
G
A
A
N
D
Honey Bee
Apis mellifera
XP_392324
916
101344
G565
N
K
W
K
G
N
T
G
D
G
N
E
S
D
S
Nematode Worm
Caenorhab. elegans
Q9TYU5
458
53125
D137
D
L
K
A
E
S
V
D
P
L
Q
A
I
S
T
Sea Urchin
Strong. purpuratus
XP_782361
504
58083
R183
P
V
P
G
C
D
S
R
G
H
F
T
G
K
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXD7
445
51348
A124
D
L
D
S
V
E
C
A
V
D
E
K
V
E
D
Baker's Yeast
Sacchar. cerevisiae
Q08649
445
52594
M124
S
R
E
N
T
D
V
M
D
L
D
N
L
N
V
Red Bread Mold
Neurospora crassa
Q7S9B6
506
58788
E185
E
I
D
M
D
E
D
E
I
P
A
A
K
K
Q
Conservation
Percent
Protein Identity:
100
75.8
N.A.
89.3
N.A.
99
99
N.A.
N.A.
97.8
93.1
76.4
N.A.
33.7
34
30.9
39.2
Protein Similarity:
100
75.8
N.A.
89.5
N.A.
99
99
N.A.
N.A.
98.5
95.9
83.4
N.A.
49.5
48.1
48.6
53.8
P-Site Identity:
100
100
N.A.
13.3
N.A.
100
100
N.A.
N.A.
100
6.6
6.6
N.A.
0
6.6
13.3
6.6
P-Site Similarity:
100
100
N.A.
46.6
N.A.
100
100
N.A.
N.A.
100
13.3
40
N.A.
0
20
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.3
31.9
31.2
Protein Similarity:
N.A.
N.A.
N.A.
50.4
47.6
47.4
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
6.6
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
7
0
0
7
20
7
0
0
% A
% Cys:
0
0
0
0
7
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
14
0
14
0
7
20
7
7
14
7
7
0
0
7
14
% D
% Glu:
40
0
20
7
7
14
7
7
0
0
7
7
40
14
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
7
% F
% Gly:
0
0
0
7
14
0
7
7
47
14
7
0
7
0
7
% G
% His:
0
7
0
7
7
0
0
0
7
7
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
0
14
0
0
0
7
0
0
% I
% Lys:
7
14
7
47
34
0
0
0
0
7
7
40
7
14
34
% K
% Leu:
0
47
0
0
0
0
0
14
0
47
0
0
7
0
7
% L
% Met:
0
7
7
7
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
7
0
7
34
0
0
7
7
7
7
14
0
% N
% Pro:
7
0
7
0
0
0
0
0
7
7
0
0
0
7
7
% P
% Gln:
0
0
0
0
0
7
7
0
0
0
7
0
0
34
7
% Q
% Arg:
0
7
34
0
7
40
0
7
7
0
0
14
7
0
0
% R
% Ser:
7
0
0
7
0
7
7
34
0
7
34
0
7
14
7
% S
% Thr:
0
0
0
7
7
7
14
7
0
0
14
14
0
0
7
% T
% Val:
7
7
7
0
14
0
14
0
7
0
0
0
7
0
7
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
14
7
0
0
0
0
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _